Dear Editor, I read the article by Wieten and colleagues1 with great interest. The authors investigated risk factors of rabies exposure among travellers. However, I have some comments concerning this study.
In line with the recommendations of World Health Organization, postexposure prophylaxis (PEP) is not indicated for category I rabies suspected contacts.2 However, ten persons in their study who received PEP had category I contact.
In their study, the median time between departure and animal-associated injury was found to be 9 days (IQR: 5-17 days). It is well known that protective antibodies against rabies vaccination begin to appear at postvaccination day 7.3 So, departure time can be scheduled at least seven days after pre-exposure prophylaxis.
Conflict of interest: none declared.
Wieten RW, Tawil S, van Vugt M, Goorhuis A, Grobusch MP. Risk of rabies exposure among travellers. Neth J Med. 2015;73:219-26.
WHO Expert Consultation on rabies: first report, October 2004.