Issue: 2007 > October > case report

A patient treated with olanzapine developing diabetes de novo: proposal for hyperglycaemia screening

M.L. Duiverman, D. Cohen, W. van Oven, P. Nieboer


We report a patient with schizophrenia who developed
diabetes mellitus during treatment with olanzapine. The
case confirms the pattern of atypical antipsychotic-related diabetic emergencies: rapid onset in relatively young patients, often with severe glucose derangements and serious complications. As diabetic emergencies have a high morbidity and mortality, regular glucose screening should be performed in patients with schizophrenia treated with atypical antipsychotics.