Granulomatous infections are commonly associated with
mycobacteria, brucellosis, actinomycosis, nocardiosis,
spirochetes, and fungi. Rarely, granuloma formation is a
host response to other bacterial infection. Osteomyelitis
and osteitis that reactivate many years after the primary
episode is a known phenomenon. A reactivation that
presents as a granulomatous disease is rare. We present a case of reactivated osteitis due to Moraxella osloensis with consecutive granuloma formation.