Issue: 2014 > July > case report

Mast cell leukaemia presenting with multiple osteoporotic fractures in an elderly woman

S.E. de Boer, K. Hoogenberg, N.K. de Boer


Osteoporotic fractures in elderly women are mainly due to postmenopausal bone loss but can sometimes be caused by a disabling haematological disease. We describe an 84-year-old woman suffering from multiple osteoporotic fractures as a manifestation of mast cell leukaemia. Mast cell leukaemia is a rare form of systemic mastocytosis with a poor prognosis and very few therapeutic options. Osteoporotic fractures have seldom been reported as its initial manifestation.