Issue: 2007 > November > case report

Disseminated intravascular coagulation and a negative D-dimer test

A.A. Constantinescu, P.B. Berendes, M-D. Levin


The diagnosis of disseminated intravascular coagulation
(DIC) requires the presence of a fibrin-related marker.
D-dimer is frequently used in clinical practice as a fibrin-related marker. We present a case of paraneoplastic
DIC with a false-negative D-dimer test. Repeating the
test using a different D-dimer assay as well as the
measurement of other fibrinolysis markers confirmed the
diagnosis of DIC.