Issue: 2011 > November/December > review

New and existing pharmacotherapeutic options for persistent asthma and COPD

Z. Diamant, S. Tarasevych, G.W. Clarke


Asthma and COPD are chronic inflammatory airway
disorders with systemic manifestations. The two diseases
have different airway inflammation, features of airway
remodelling with subsequent pathophysiology and clinical
presentation. The international management guidelines
recommend stepwise pharmacotherapy depending on
disease control and/or disease stage, comprising relievers and overall uniform controller treatment, despite the heterogeneity across the conditions and treatment response. Despite effective medications per se, still too many patients remain uncontrolled and no treatment can definitely cure either of the conditions. This overview includes currently recommended pharmacotherapeutic options with novel and future treatment targets.