Encapsulating peritoneal sclerosis (EPS) is an uncommon
but one of the most serious complications in patients on
long-term peritoneal dialysis. EPS is characterised by a diffuse thickening and/or sclerosis of the peritoneal membrane which leads to a decreased ultrafiltration and
ultimately to bowel obstruction. We present four cases of
EPS and discuss the clinical manifestations, multifactorial
aetiology, diagnosis, treatment, prognosis, and prevention. We end with a proposal for the development of an EPS prevention guideline.