Issue: 2006 > April > case report

Fibrillary glomerulonephritis in a patient with type 2 diabetes mellitus

G.A.L. Gielen, J.F.M. Wetzels, E.J. Steenbergen, A.H. Mudde


we report a 62-year-old man with documented type 2
diabetes mellitus and hypertension, who presented with
a rapid deterioration in renal function. The sudden
decrease in renal function in this well-controlled diabetic
patient prompted us to consider a nondiabetic and
nonhypertensive cause. The urinary sediment showed a
glomerular haematuria suggestive of glomerulonephritis.
A diagnosis of fibrillary glomerulonephritis was made
on renal biopsy. fibrillary glomerulonephritis is a rarely
diagnosed disease with clinical manifestations such as
proteinuria, microscopic haematuria, nephrotic syndrome and impairment of renal function. A diagnosis of fibrillary glomerulonephritis can only be made by electronmicroscopy of the renal tissue. in this case report the spectrum of this disease is reviewed.