Issue: 2006 > March > case report

Pleural thickening in a construction worker: it is not always mesothelioma

M.D. Saboerali, M.G.J. Koolen, L.A. Noorduyn, O.M. van Delden, H.J. Bogaard


We describe the case of a 45-year-old man presenting with chest pain and pleural effusions. These symptoms were progressive over a period of three years, with pericardial involvement and respiratory insufficiency finally resulting in death. Despite repeated diagnostic procedures, a final diagnosis could only be made at autopsy. Multisystem foamy histiocyte infiltration suggested the diagnosis of Erdheim-Chester disease.