Issue: 2020 > April > case report

FSGS tip lesion in polyautoimmunity including Sjögren’s syndrome

E.A. Lucassen, T. Vlasveld, N. Hommes
AbstractFull textPDF


We present a case with five auto-immune phenomena, including Sjögren’s syndrome, for which we also diagnosed a tip lesion of focal segmental glomerulosclerosis (FSGS).v About one-third of Sjögren’s syndrome patients have renal involvement, but FSGS is rarely reported. FSGS is thought to involve T-cell dysfunction and in this patient with multiple auto-immune phenomena, it may reflect a severe dysregulation of cellular immunity.