Issue: 2018 > December > case report

Macrophage activation syndrome with lung involvement complicating adult-onset Still's disease

C.R. Wang, Y.S. Tsai, I.C. Ma
AbstractFull textPDF


Adult-onset Still's disease (AOSD) can progress into macrophage activation syndrome (MAS), which may be fatal. We report on a 19-year-old Han Chinese female, who presented with MAS-related pulmonary parenchymal involvement complicating AOSD, and further associated with disseminated intravascular coagulation and generalized tonic-clonic seizure. She was managed by high-dose corticosteroids and pulse cyclophosphamide therapy with a complete recovery of disease activity.