Electrolyte disorders are common and often challenging in
terms of differential diagnosis and appropriate treatment.
To facilitate this, the first Dutch guideline was developed in
2005, which focused on hypernatraemia, hyponatraemia,
hyperkalaemia, and hypokalaemia. This guideline was
recently revised. Here, we summarise the key points of
the revised guideline, including the major complications
of each electrolyte disorder, differential diagnosis and
recommended treatment. In addition to summarising
the guideline, the aim of this review is also to provide
a practical guide for the clinician and to harmonise the
management of these disorders based on available evidence and physiological principles.