Issue: 2011 > May > review

Malignancies associated with chronic hepatitis C: case report and review of the literature

A.P.J. Vlaar, S.T. Rietdijk, S.S. Zeerleder, T. Boerman, U. Beuers


Hepatocellular carcinoma (HCC) is a well-known
consequence of hepatitis C virus (HCV) infection mainly in cirrhotic patients. Associations of other malignancies such as cholangiocellular carcinoma and B-cell malignancies with HCV are less well known. Here we review pathophysiological aspects of malignancies associated with HCV infection. A case report of HCV-related HCC and B-cell lymphoma illustrates the increased risk for HCV-infected patients to develop other malignancies besides HCC.