Issue: 2011 > March > case report

Mastocytosis and diffuse large B-cell lymphoma, an unlikely combination

E.M. Schipper, W. Posthuma, I. Snieders, R.E. Brouwer


Systemic mastocytosis may be accompanied by a second
haematological malignancy, usually of myeloid origin.
However, a number of case reports describe systemic
mastocytosis coexisting with a second haematological
malignancy of lymphoid origin. Here, we report a case of a 74-year-old man with systemic mastocytosis who developed a diffuse large B-cell lymphoma. A short overview of the literature concerning mastocytosis accompanied by a second haematological malignancy is presented.