Issue: 2009 > February > case report

Ceftriaxone-induced acute reversible encephalopathy in a patient treated for a urinary tract infection

R. Roncon-Albuquerque Jr, I. Pires, R. Martins, R. Real, G. Sousa, P. von Hafe


Encephalopathy is a rare side effect of third- and
fourth-generation cephalosporins. Renal failure and
previous disease of the central nervous system predispose to this neurotoxicity. We describe a case of encephalopathy with generalised triphasic waves in a patient with pre-existent cerebrovascular disease who was treated with ceftriaxone for a urinary tract infection. Early recognition of this complication is relevant given that ceftriaxone discontinuation reverted the neurological syndrome.